Fitness
The combined association of physical activity and alcohol use with long-term mortality: an age-stratified analysis – BMC Public Health
![The combined association of physical activity and alcohol use with long-term mortality: an age-stratified analysis – BMC Public Health The combined association of physical activity and alcohol use with long-term mortality: an age-stratified analysis – BMC Public Health](https://static-content.springer.com/image/art%3A10.1186%2Fs12889-024-19326-8/MediaObjects/12889_2024_19326_Fig1_HTML.png)
Chudasama YV, Khunti K, Gillies CL, Dhalwani NN, Davies MJ, Yates T, et al. Healthy lifestyle and life expectancy in people with multimorbidity in the UK Biobank: a longitudinal cohort study. PLoS Med. 2020;17(9):e1003332.
Li Y, Schoufour J, Wang DD, Dhana K, Pan A, Liu X, et al. Healthy lifestyle and life expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study. BMJ. 2020;368:l6669.
Li Y, Pan A, Wang DD, Liu X, Dhana K, Franco OH, et al. Impact of healthy lifestyle factors on life expectancies in the US Population. Circulation. 2018;138(4):345–55.
Li K, Husing A, Kaaks R. Lifestyle risk factors and residual life expectancy at age 40: a German cohort study. BMC Med. 2014;12:59.
Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020;54(24):1451–62.
Tucker WJ, Fegers-Wustrow I, Halle M, Haykowsky MJ, Chung EH, Kovacic JC. Exercise for primary and secondary Prevention of Cardiovascular Disease: JACC Focus Seminar 1/4. J Am Coll Cardiol. 2022;80(11):1091–106.
Piercy KL, Troiano RP, Ballard RM, Carlson SA, Fulton JE, Galuska DA, et al. The physical activity guidelines for americans. JAMA. 2018;320(19):2020–8.
Moore SC, Patel AV, Matthews CE, Berrington de Gonzalez A, Park Y, Katki HA, et al. Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysis. PLoS Med. 2012;9(11):e1001335.
Moissl AP, Delgado GE, Kramer BK, Dawczynski C, Stojakovic T, Marz W, et al. Alcohol consumption and mortality: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. Atherosclerosis. 2021;335:119–25.
Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA. Association of Alcohol Consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis. BMJ. 2011;342:d671.
Zhao J, Stockwell T, Naimi T, Churchill S, Clay J, Sherk A. Association between Daily Alcohol Intake and Risk of all-cause mortality: a systematic review and Meta-analyses. JAMA Netw Open. 2023;6(3):e236185.
French MT, Popovici I, Maclean JC. Do alcohol consumers exercise more? Findings from a national survey. Am J Health Promot. 2009;24(1):2–10.
Wynne JL, Wilson PB. Got Beer? A systematic review of Beer and Exercise. Int J Sport Nutr Exerc Metab. 2021;31(5):438–50.
Levitt DE, Luk HY, Vingren JL, Alcohol. Resistance Exercise, and mTOR pathway signaling: an evidence-based narrative review. Biomolecules. 2022;13(1).
Duplanty AA, Budnar RG, Luk HY, Levitt DE, Hill DW, McFarlin BK, et al. Effect of Acute Alcohol Ingestion on Resistance Exercise-Induced mTORC1 Signaling in Human muscle. J Strength Cond Res. 2017;31(1):54–61.
Leasure JL, Neighbors C, Henderson CE, Young CM. Exercise and Alcohol Consumption: what we know, what we need to know, and why it is important. Front Psychiatry. 2015;6:156.
Ashdown-Franks G, Firth J, Carney R, Carvalho AF, Hallgren M, Koyanagi A, et al. Exercise as Medicine for Mental and Substance Use disorders: a Meta-review of the benefits for neuropsychiatric and cognitive outcomes. Sports Med. 2020;50(1):151–70.
Hallgren M, Vancampfort D, Hoang MT, Andersson V, Ekblom O, Andreasson S, et al. Effects of acute exercise on craving, mood and anxiety in non-treatment seeking adults with alcohol use disorder: an exploratory study. Drug Alcohol Depend. 2021;220:108506.
Gunillasdotter V, Andreasson S, Hallgren M, Jirwe M. Exercise as treatment for alcohol use disorder: a qualitative study. Drug Alcohol Rev. 2022;41(7):1642–52.
Collaborators GBDA. Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the global burden of Disease Study 2020. Lancet. 2022;400(10347):185–235.
Angus C. Harms of alcohol in different age groups. BMJ. 2022;378:o1979.
Dodge T, Clarke P, Dwan R. The relationship between physical activity and alcohol use among adults in the United States. Am J Health Promot. 2017;31(2):97–108.
Izquierdo M, Merchant RA, Morley JE, Anker SD, Aprahamian I, Arai H, et al. International Exercise recommendations in older adults (ICFSR): Expert Consensus guidelines. J Nutr Health Aging. 2021;25(7):824–53.
Eijsvogels TM, Molossi S, Lee DC, Emery MS, Thompson PD. Exercise at the extremes: the amount of Exercise to Reduce Cardiovascular events. J Am Coll Cardiol. 2016;67(3):316–29.
Lee DH, Rezende LFM, Joh HK, Keum N, Ferrari G, Rey-Lopez JP, et al. Long-term leisure-time physical activity intensity and all-cause and cause-specific mortality: a prospective cohort of US adults. Circulation. 2022;146(7):523–34.
Fernandez-Sola J. Cardiovascular risks and benefits of moderate and heavy alcohol consumption. Nat Rev Cardiol. 2015;12(10):576–87.
Goel S, Sharma A, Garg A. Effect of Alcohol Consumption on Cardiovascular Health. Curr Cardiol Rep. 2018;20(4):19.
O’Keefe EL, DiNicolantonio JJ, O’Keefe JH, Lavie CJ. Alcohol and CV Health: Jekyll and Hyde J-Curves. Prog Cardiovasc Dis. 2018;61(1):68–75.
Xi B, Veeranki SP, Zhao M, Ma C, Yan Y, Mi J. Relationship of Alcohol Consumption to All-Cause, Cardiovascular, and Cancer-related mortality in U.S. adults. J Am Coll Cardiol. 2017;70(8):913–22.
Di Castelnuovo A, Costanzo S, Bonaccio M, Rago L, De Curtis A, Persichillo M, et al. Moderate alcohol consumption is Associated with Lower risk for heart failure but not atrial fibrillation. JACC Heart Fail. 2017;5(11):837–44.
Goncalves A, Claggett B, Jhund PS, Rosamond W, Deswal A, Aguilar D, et al. Alcohol consumption and risk of heart failure: the atherosclerosis risk in communities Study. Eur Heart J. 2015;36(15):939–45.
Bell S, Daskalopoulou M, Rapsomaniki E, George J, Britton A, Bobak M, et al. Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records. BMJ. 2017;356:j909.
Aberg F, Byrne CD, Pirola CJ, Mannisto V, Sookoian S. Alcohol consumption and metabolic syndrome: clinical and epidemiological impact on liver disease. J Hepatol. 2023;78(1):191–206.
Csengeri D, Sprunker NA, Di Castelnuovo A, Niiranen T, Vishram-Nielsen JK, Costanzo S, et al. Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes. Eur Heart J. 2021;42(12):1170–7.
Andersson C, Schou M, Gustafsson F, Torp-Pedersen C. Alcohol intake in patients with cardiomyopathy and heart failure: Consensus and controversy. Circ Heart Fail. 2022;15(8):e009459.
Rumgay H, Murphy N, Ferrari P, Soerjomataram I. Alcohol and Cancer: Epidemiology and Biological mechanisms. Nutrients. 2021;13(9).
Suter F, Pestoni G, Sych J, Rohrmann S, Braun J. Alcohol consumption: context and association with mortality in Switzerland. Eur J Nutr. 2023;62(3):1331–44.
Day E, Rudd JHF. Alcohol use disorders and the heart. Addiction. 2019;114(9):1670–8.
Stockwell T, Zhao J, Panwar S, Roemer A, Naimi T, Chikritzhs T. Do moderate drinkers have reduced mortality risk? A systematic review and Meta-analysis of Alcohol Consumption and all-cause mortality. J Stud Alcohol Drugs. 2016;77(2):185–98.
Krittanawong C, Isath A, Rosenson RS, Khawaja M, Wang Z, Fogg SE, et al. Alcohol Consumption and Cardiovascular Health. Am J Med. 2022;135(10):1213–30. e3.
Fiuza-Luces C, Santos-Lozano A, Joyner M, Carrera-Bastos P, Picazo O, Zugaza JL, et al. Exercise benefits in cardiovascular disease: beyond attenuation of traditional risk factors. Nat Rev Cardiol. 2018;15(12):731–43.
Damluji AA, Alfaraidhy M, AlHajri N, Rohant NN, Kumar M, Al Malouf C, et al. Sarcopenia Cardiovasc Dis Circulation. 2023;147(20):1534–53.
Piano MR. Alcohol’s effects on the Cardiovascular System. Alcohol Res. 2017;38(2):219–41.
Bodine SC, Stitt TN, Gonzalez M, Kline WO, Stover GL, Bauerlein R, et al. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol. 2001;3(11):1014–9.
Drummond MJ, Fry CS, Glynn EL, Dreyer HC, Dhanani S, Timmerman KL, et al. Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis. J Physiol. 2009;587(Pt 7):1535–46.
Parr EB, Camera DM, Areta JL, Burke LM, Phillips SM, Hawley JA, et al. Alcohol ingestion impairs maximal post-exercise rates of myofibrillar protein synthesis following a single bout of concurrent training. PLoS ONE. 2014;9(2):e88384.
Steiner JL, Lang CH. Alcohol impairs skeletal muscle protein synthesis and mTOR signaling in a time-dependent manner following electrically stimulated muscle contraction. J Appl Physiol (1985). 2014;117(10):1170–9.
Steiner JL, Lang CH. Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction. Alcohol Clin Exp Res. 2015;39(1):1–10.